Metformin Compared to Glyburide in Gestational Diabetes

• Status: Completed
• Trial end date: 2008-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

Our hypothesis is that metformin and glyburide will have equal efficacy in controlling blood glucose in gestational diabetics with no increase in adverse maternal, fetal or neonatal outcomes.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of New Mexico
• Treatments: Glyburide; Metformin

Criteria

Inclusion Criteria:

• Gestational diabetes not controlled with diet and exercise

Exclusion Criteria:

• history of alcohol misuse

• history of drug misuse

• Chronic hypertension requiring medication

• Renal failure

• Hepatic disease or dysfunction

• Known fetal anomaly

• Inability to give consent

• known allergy to metformin or glyburide