Overview

Metformin Effect on Brain Function in Insulin Resistant Elderly People

Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
Participant gender:
Summary
Alzheimer's disease (AD) and other forms of dementia are rapidly increasing with the aging of the population, and show a clear preponderance among people with insulin resistance. Metformin, an insulin sensitizer, is being examined in clinical trials as an anti-aging drug. However, very little objective data is available regarding metformin's effect on the brain, a major organ affected by aging.
Phase:
Phase 2
Details
Lead Sponsor:
Mayo Clinic
Collaborator:
National Institute on Aging (NIA)
Treatments:
Insulin
Metformin