Metformin Use and Clinical Pregnancy Rate in Women With Unexplained Infertility

• Status: Unknown status
• Trial end date: 2019-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to asses the effect of metformin on clinical pregnancy rate in women with unexplained infertility (randomized controlled trial).

This study will be conducted in infertility clinic,Ain Shams university maternity hospital,170 women with unexplained infertility will be enrolled in this study.

Statistical analysis of the data will be performed .

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Elham Raafat
• Treatments: Citric Acid; Clomiphene; Enclomiphene; Metformin; Sodium Citrate; Zuclomiphene

Criteria

Inclusion Criteria:

• Age 20-35 years old.

• BMI 20-<30

• FSH 12 IU/L or less

• Normal transvaginal ulterasound(normal uterus and ovaries with no congenital anomalies).

• Patent fallopian tubes assesd by hysterosalpingogram or laparoscopy.

• Normal semen analysis.

• Infertile women with history of previous failed induction cycle.

Exclusion Criteria:

• Women younger than 20 or elder than 35 years old.

• Women with BMI equal to or more than 30.

• Uncorrected congenital or acquired uterine anomaly.

• Other causes of infertility rather than unexplained infertility.

• Patient with Diabetes Mellitus.