Metformin Versus Acarbose Treatment in Infertile Overweight Women With Polycystic Ovary Syndrome (PCOS)

• Status: Completed
• Trial end date: 2008-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study is a prospective randomized clinical trial to compare the endocrine and metabolic effects of two anti diabetic drugs (metformin vs. acarbose) in infertile overweight women with PCOS

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Royan Institute
• Treatments: Acarbose; Metformin

Criteria

Inclusion Criteria:

• Poly Cystic Ovarian Syndrome patients

• Age < 40 years

• BMI > 25 kg/m2

Exclusion Criteria:

• Smoking

• Overt diabetes mellitus, hyperprolactinemia, diseases that would disturb clinical and hormonal responses (adrenal disease or tumors, ovarian tumors, thyroid disease)

• The use of hormonal medications or drugs that might interfere with carbohydrate metabolism over the last 6 months.