Metformin Versus Insulin in Pregnant Women With Type 2 Diabetes
Status:
Completed
Trial end date:
2011-08-01
Target enrollment:
Participant gender:
Summary
Pregnant women with type 2 diabetes mellitus (T2DM) are at increased risk for miscarriages,
birth defects, large infants, and stillbirths. Maintaining blood sugars in the normal range
decreases these pregnancy complications. We hypothesize that metformin will achieve similar
levels of blood sugar control compared to insulin. In doing so, metformin will prevent the
increased risk of pregnancy complications associated with T2DM in pregnancy. We propose a
pilot study of a randomized, controlled trial of metformin versus insulin in the treatment of
T2DM during pregnancy.
Phase:
N/A
Details
Lead Sponsor:
The University of Texas Health Science Center, Houston