Metformin and Folate in Pregnant Polycystic Ovary Syndrome(PCOS) Women

• Status: Completed
• Trial end date: 2011-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

A more recent prospective nonrandomized placebo-controlled double-blind clinical study demonstrated that metformin exerts a slight but significant deleterious effect on serum homocysteine (Hcy) levels in patients with PCOS, and supplementation with folate is useful to increase the beneficial effect of metformin on the vascular endothelium.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Magna Graecia
• Treatments: Folic Acid; Metformin; Vitamin B Complex

Criteria

Inclusion Criteria:

• Pregnancy

• PCOS

Exclusion Criteria:

• Risk factors for pregnancy complications

• Severe obesity