Metformin and Lactoferrin in Sepsis in Icu

• Status: Recruiting
• Trial end date: 2024-06-09
• Target enrollment: 0
• Participant gender: All

Summary

Sepsis is a life-threatening organ dysfunction triggered by an unregulated response of a host to infection. Sepsis is a reason for substantial mortality and morbidity among intensive care unit (ICU) patients. 1 Therefore, the aim of our study is to compare the safety and efficacy of metformin and lactoferrin in ICU patients with sepsis.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tanta University
• Treatments: Lactoferrin; Metformin

Criteria

Inclusion Criteria:

• Inclusion Criteria:

1. Age more than 18 years old.

2. A diagnosis of sepsis according to the latest Sepsis definition.11

3. Estimated GFR >45 ml/minute.

Exclusion Criteria:

Exclusion Criteria:

1. Pregnancy and breast feeding.

2. End stage hepatic disease.

3. End stage renal disease -