Metformin for Weight Loss in Schizophrenia

• Status: Terminated
• Trial end date: 2011-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Study hypothesis is that patients on antipsychotics medication treated with metformin will show loss in weight and improved measures of glucose metabolism.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nathan Kline Institute for Psychiatric Research
• Treatments: Antipsychotic Agents; Metformin

Criteria

Inclusion Criteria:

• Patients will be 18-70 years of age;

• Currently hospitalized or an outpatient at MPC;

• BMI ≥ 35 or excessive recent weight gain ( > than 10 lb weight gain in the past 3 months);

• Patients will have a diagnosis of schizophrenia or schizoaffective disorder or bipolar disorder.

Exclusion Criteria:

• Age below 18 or over 70;

• Patient is currently already treated with metformin.