Overview Metformin's Effect on Glucagon-induced Glucose Production and Protein Metabolism. Status: Completed Trial end date: 2016-03-01 Target enrollment: Participant gender: Summary This study is being done to understand metformin's mechanisms of action regarding glucose production, protein metabolism, and mitochondrial function. Phase: Phase 1 Details Lead Sponsor: Mayo ClinicTreatments: GlucagonLactuloseMetformin