Methadone in Pediatric Anesthesiology II

• Status: Completed
• Trial end date: 2018-06-30
• Target enrollment: 0
• Participant gender: All

Summary

Three arm randomized controlled trial to evaluate the efficacy of a single dose of intraoperative methadone in reducing post-operative pain and opioid consumption in adolescents undergoing posterior spinal fusion. Our secondary goal is to determine the pharmacokinetics of IV methadone in children (0.3 and 0.4 mg/kg).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Washington University School of Medicine
• Treatments: Methadone

Criteria

Inclusion Criteria.

• Age 11-18 years

• Undergoing general anesthesia and idiopathic posterior spinal surgery with anticipated postop inpatient stay of > 3 days

• Signed, written, informed consent from legal guardians and assent from patient

Exclusion Criteria.

• History of or known liver or kidney disease.

• Females who are pregnant or nursing.

• Children with developmental delay

• Children undergoing surgery for scoliosis of musculoskeletal origin