Methocarbamol in Treatment of Muscle Cramps in Cirrhotic Patients

• Status: Unknown status
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Muscle cramps markedly affect the quality of life in cirrhotic patients with no highly effective drug. Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. The mechanism of action of methocarbamol is currently unknown, but may involve the inhibition of carbonic anhydrase. Methocarbamol has a high therapeutic index, i.e. a wide range of safe and effective dosages.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tanta University
• Treatments: Calcium; Calcium Carbonate; Calcium, Dietary; Methocarbamol

Criteria

Inclusion Criteria:

• Cirrhotic patients with frequent muscle cramps.

Exclusion Criteria:

• Elderly patients.

• Encephalopathy