Methotrexate For The Prevention and Treatment of Proliferative Vitreoretinopathy in Pediatric Patients
Status:
Not yet recruiting
Trial end date:
2024-04-01
Target enrollment:
Participant gender:
Summary
Rhegmatogenous retinal detachment (RRD) is a sight-threatening condition. Children with RRD
usually present late with clinical features of longstanding RRD, specifically a serious
condition named: proliferative vitreoretinopathy (PVR). Therefore, children with RRD often
have poorer outcomes. The objective of this study is to investigate the efficacy and safety
of methotrexate in the treatment and prevention of PVR. Methotrexate is a medication that has
been used to treat inflammatory conditions in children and adults for a long time and it has
been recently used to treat PVR in adults.