Methotrexate in the Treatment of Chronic Idiopathic Urticaria
Status:
Completed
Trial end date:
2016-05-01
Target enrollment:
Participant gender:
Summary
Chronic urticaria is defined by urticarial lesions persisting at 6 weeks. The cause is not
found in about 75% of cases (chronic idiopathic urticaria). The gold standard treatment
consists of anti-H1 molecules. In severe cases, refractory to anti-H1, few therapeutic
alternatives exist. Methotrexate, which is not expensive and often prescribed by
dermatologists, has been efficiently tried in an open study on severe chronic idiopathic
urticaria, and also in few case reports.