Methylphenidate Treatment for Cocaine Abuse and ADHD - 1

• Status: Completed
• Trial end date: 2004-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Many cocaine dependent individuals are also diagnosed with Attention Deficit Hyperactivity Disorder (ADHD). Methylphenidate (Ritalin) is currently approved to treat individuals diagnosed with ADHD. The purpose of this study is to determine the effectiveness of methylphenidate in treating ADHD symptoms in cocaine dependent individuals.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: New York State Psychiatric Institute
• Collaborator: National Institute on Drug Abuse (NIDA)
• Treatments: Cocaine; Methylphenidate

Criteria

Inclusion Criteria:

• Meets DSM-IV criteria for cocaine dependence

• Meets DSM-IV criteria for persistent adult Attention Deficit Hyperactive Disorder

Exclusion Criteria:

• Meets DSM-IV criteria for current psychiatric disorders (other than ADHD or substance abuse) that requires a psychiatric intervention

• Physiologically dependent on sedatives or alcohol, to the extent that medical attention is required during periods of abstinence or significant reduction in the amount of use

• Exhibits suicidal or homicidal behavior within the two years prior to enrollment

• Currently taking prescription psychotropic medication

• Unstable medical condition (e.g., uncontrolled diabetes) that would make participation in the study hazardous

• Known sensitivity to methylphenidate

• Pregnant or breastfeeding