The goal of this study is to determine whether use of promotility agents to stimulate gastric
peristalsis can reduce fluoroscopy time and procedure time during gastrojejunostomy (GJ)
tubes placement in interventional radiology (IR). The investigators hypothesize that
increased gastric peristalsis will aid in advancing a guidewire through the pylorus, a time
consuming and tedious step required during GJ tube placement. In order to maximize scientific
rigor and clinical practice impact, the investigators aim to answer this question through a
blinded, randomized, placebo controlled trial.
Specific Aim 1: To test the hypothesis that a single dose of IV metoclopramide immediately
prior to GJ tube placement reduces the fluoroscopy time required to advance a guidewire
through the pylorus.
Specific Aim 2: To determine whether a single dose of IV metoclopramide immediately prior to
GJ tube placement reduces total procedure fluoroscopy time, air kerma and total procedure
time.
Specific Aim 3: To assess the safety of a single dose of promotility agent prior to GJ tube
placement by assessing rates of adverse events in the periprocedural period in patients
receiving IV metoclopramide versus placebo.