Metoclopramide for Gastric Visualization in Active Upper GI Bleeding
Status:
Recruiting
Trial end date:
2025-06-30
Target enrollment:
Participant gender:
Summary
This study aim to evaluate the efficacy of metoclopramide for gastric visualization in
patients with active UGIB. This is a double-blinded, multicenter RCT. Patients with 'active'
UGIB (hematemesis or presence of fresh blood in the nasogastric tube) were enrolled. The
eligible patients were randomly assigned in a concealed 1:1 allocation to received either
intravenous metoclopramide or placebo before endoscopy. The primary outcome was 'adequate
visualization' by objective endoscopic visualized scores(EVS). Secondary outcomes included
mean difference in total EVS and EVS at each location , duration of EGD, immediate
hemostasis, need for a second look EGD, units of blood transfusion, length of hospital stay
and 30-day rebleeding rate.