Microwave Ablation Combined With Chemotherapy for Colorectal Liver Metastases： a Multicenter Cohort Study
Status:
Not yet recruiting
Trial end date:
2026-09-01
Target enrollment:
Participant gender:
Summary
Colorectal cancer is the second deadliest malignant tumor worldwide, and liver is the most
common site of hematogenic metastasis of Colorectal cancer. Surgery is an effective treatment
for colorectal cancer with liver metastasis, however, only 10%-20% of patients with liver
metastasis are feasible for radical surgical resection. Many single-center retrospective
studies have demonstrated that thermal ablation for liver metastases is comparable to
surgery. Chemotherapy can kill the microscopic cancer foci of the liver. The timing of
ablation-related chemotherapeutic administration still needs to be explained.
The purpose of this study was to compare the clinical efficacy of thermal ablation or
combined with perioperative chemotherapy and postoperative chemotherapy in the treatment of
colorectal cancer with liver metastasis.