Minimal Opioid Use After Total Hip Replacement (THR)
Status:
Completed
Trial end date:
2019-09-27
Target enrollment:
Participant gender:
Summary
Total hip arthroplasty can be associated with significant postoperative pain. Side effects of
pain management may impair participation in physical therapy and slow readiness for discharge
from the hospital. In a previous study done by the investigators' group, epidural patient
controlled analgesia (EPCA) with a hydromorphone containing solution appeared to have a more
favorable pain profile with ambulation, but greater side effects compared to injection of a
peri-articular cocktail. The use of opioid was greater in the peri-articular injection group
(PAI). There was no difference in length of stay. In view of the controversy over opioid use,
the investigators would like to develop an optimal opioid sparing pain management approach by
comparing 3 different protocols 1) Plain local anesthetic EPCA; 2) PAI; 3) EPCA + PAI; all in
conjunction with a multimodal opioid sparing pain regimen. The goal would be to maximize pain
control while minimizing opioid use and side-effects.