Minimal Stimulation Protocol Using Aromek(Letrozole) and Follitrope(recFSH) Combined With INVOCell-Low Cost IVF

• Status: Unknown status
• Trial end date: 0000-00-00
• Target enrollment: 100
• Participant gender: Both

Summary

The purpose of this study to evaluate a low cost minimal stimulation protocol combined with Intravaginal Culturing, to make IVF affordable and available across the large infertile/subfertile population

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Galaxy Pharma (Pvt) Limited
• Collaborators: AMERICAN IVF & PREGNANCY CENTRE - KARACHI; Fertility Care Multan; FRIENDS IVF, Faisalabad; Galaxy IVF
• Treatments: Letrozole
• Last Updated: 2011-02-06

Criteria

Inclusion Criteria:

• Tubal factor without Hydrosalpinx

• Unexplained infertility with unsuccessful attempts in achieving pregnancy through timed intercourse or IUI

• Boarder line male factor infertility

• Sperm DNA Fragmentation < 30%

• Normal Uterine Cavity

• Normal baseline ultrasound with adequate number of primary follicles present

• Normal FSH and E2 on Day 3

• Age of the female is < 35 years old

Exclusion Criteria:

• If previous IVF or INVO attempts resulted in failed fertilisation

• Male partner who has difficulty in producing semen sample

• Very low sperm count, very low percentage of sperm motility and morphology

• Sperm DNA Fragmentation > 30%

• Age of female patient > 37 years

• Borderline or elevated E2 or FSH on day 3 or failed CCCT or low blood inhibin levels

• Poor ovarian response

• Hydrosalpinx

• Anatomic difficulties in reaching ovaries for oocyte retrieval

• Cervical stenosis, making embryo transfer difficult

• Uterine abnormalities or deformities

• Obesity