Minimizing Nausea and Vomiting During Spinals for CS

• Status: Terminated
• Trial end date: 2016-11-30
• Target enrollment: 0
• Participant gender: Female

Summary

In parturients undergoing Cesarean section under spinal anesthesia, co-loading of 1 liter of crystalloids, with placing the spinal, along with administering a phenylephrine infusion and glycopyrrolate, enables placing a spinal with minimal perioperative nausea and vomiting and good intra and post-operative pain relief.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Kokila N Thenuwara; University of Iowa
• Treatments: Glycopyrrolate

Criteria

Inclusion Criteria:

1. Pregnant

2. American Society of Anesthesiologists risk classification I and II

3. Age > 18 years

4. Non-laboring

5. Patients with elective cesarean sections

Exclusion Criteria:

1. Non- English speakers

2. Height < 4' 11"

3. BMI >40 Kg/ mm

4. Antiemetic drug use in the 24 hours prior to cesarean delivery,

5. Hypertensive diseases of pregnancy

6. Chronic hypertension receiving antihypertensive treatment

7. Any other physical or psychiatric condition that may impair their ability to cooperate with study data collection.