Minimum Effective Concentration of Bupivacaine in Ultrasound-guided Axillary Brachial Plexus Block

• Status: Completed
• Trial end date: 2012-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Background: The use of ultrasound in regional anesthesia enables a reduction in the local anesthetic volume. The present study aimed to determine the minimum effective concentration (EC50 and EC95) of bupivacaine for axillary brachial plexus block (ABPB). Methods: Following approval by the Research Ethics Committee, patients with a physical condition of I or II according to the American Society of Anesthesiologists, between 21 and 65 years of age were recruited and subjected to elective surgery of the hand and ABPB. The concentration of the anesthetic was determined using a step-up/step-down method and was based on the outcome of the preceding block.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Federal University of São Paulo
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

• patients with a physical condition of I or II according to the American Society of Anesthesiologists,

• between 18 and 65 years of age

• unilateral hand surgery

• BMI< 35 kg;m@

Exclusion Criteria:

• contraindication to regional anesthesia

• bleeding diathesis

• inability to visualize one or more nerves in the axilla

• psychiatric history