Minimum Effective Volume of 0.375% Bupivacaine in Interscalene Brachial Plexus Block
Status:
Unknown status
Trial end date:
2013-09-01
Target enrollment:
Participant gender:
Summary
The use of ultrasound in regional anesthesia enables reduction in the local anesthetic
volume. The present study aimed to determine the minimum effective volume of 0.375%
bupivacaine with epinephrine for interscalene brachial plexus block for shoulder surgery.
Following approval by the Research Ethics Committee, patients with a physical condition of I
or II according to the American Society of Anesthesiologists, between 21 and 65 years old and
subjected to elective surgery of the shoulder and interscalene brachial plexus block will be
recruited. The volume of the anesthetic will be determined using a step-up/step-down method
and based on the outcome of the preceding block. Positive or negative block results in a 1mL
reduction or increase in volume, respectively. The success of the block is defined as the
presence of motor block in two muscle groups and the absence of thermal and pain sensations
in the necessary dermatomes within 30 minutes of the injection. Diaphragmatic paralysis,
pulmonary function and analgesia will be quantified at 30 minutes, 4 and 6 hours. Data will
undergo statistical analysis in order to determine minimum effective volume of 0.375%
bupivacaine and, secondarily, the maximum volume that maintains the diaphragmatic function,
evaluate diaphragm paralysis and its influence in pulmonary function.