Mirtazapine vs Sumatriptan in the Treatment of Postdural Puncture Headache
Status:
Not yet recruiting
Trial end date:
2022-11-15
Target enrollment:
Participant gender:
Summary
Postdural puncture headache (PDPH) is a potential complication after spinal anesthesia caused
by traction on pain-sensitive structures from low cerebrospinal fluid pressure (intracranial
hypotension) following a leak of cerebrospinal fluid at the puncture site. Symptoms of this
condition include a bilateral frontal or occipital headache that is worse in the upright
position, along with nausea, neck pain, dizziness, visual changes, tinnitus, hearing loss, or
radicular symptoms in the arms.
This study will examine the efficacy of mirtazapine in in the treatment of PDPH after
obstetric surgery under spinal anesthesia and compared its efficacy with that of sumatriptan.