Overview

Misoprostol Administration Before Operative Hysteroscopy

Status:
Completed

Trial end date:
2014-02-01

Target enrollment:
0

Participant gender:
Female

Summary

The objective of this study is to compare the efficacy of oral, sublingual, vaginal, and no misoprostol prior to operative hysteroscopy in premenopausal women.

Phase:

Phase 3

Accepts Healthy Volunteers?

Details

Lead Sponsor:

CHA University

Treatments:

Misoprostol

Criteria

Inclusion Criteria:

Symptomatic patients that were suspected as having intrauterine pathology, such as
submucosal myoma, endometrial polyp or other endometrial pathological findings based on the
transvaginal ultrasound, were enrolled.

Inclusion criteria were as follows: women who were of reproductive age (i.e., were
premenopausal) and were not pregnant at the time of presentation (i.e., negative for urine
pregnancy test or last menstrual period within the last 4 weeks). -

Exclusion Criteria:

Exclusion criteria included any evidence of a contraindication to prostaglandins (history
of severe asthma, glaucoma, preexisting severe cardiac disease, or renal failure), or
allergy to prostaglandins, any sign of genital infection, presence of significant
uterovaginal prolapse that could affect administration of vaginal tablets, history of
cervical surgery, presence of space occupying lesions in endocervical canal, and treatment
of GnRH agonist.