Misoprostol Versus Dilapan-S for Cervical Preparation

• Status: Completed
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to compare the dilatory effect of 400 mcg of buccally administered misoprostol to one Dilapan-S rod placed 3-4 hours before abortion by dilation and evacuation in women who are 12 weeks 0 days to 15 weeks 0 days gestation.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Planned Parenthood League of Massachusetts
• Collaborator: Society of Family Planning
• Treatments: Hydroxocobalamin; Misoprostol; Vitamin B 12; Vitamin B Complex; Vitamins

Criteria

Inclusion Criteria:

• medically eligible for dilation and evacuation at Planned Parenthood League of Massachusetts

• gestational age 12 weeks 0 days to 15 weeks 0 days as evaluated by ultrasound

• proficient in English or Spanish

• agreeing to study procedures, including randomization and surveys regarding demographics, medical and gynecological history, and assessments of pain and satisfaction

Exclusion Criteria:

• less than 18 years old

• cervical or uterine anomaly that the research physician deems may affect the difficulty of dilation or the abortion procedure

• inflammatory bowel disease

• contraindication to misoprostol use

• known intolerance or allergy to misoprostol or Dilapan-S

• inability to give informed consent