Misoprostol Versus Effox as Cervical Ripening Agent Prior Surgical Evacuation
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Ninety healthy pregnant women candidate for surgical evacuation after confirming 1st
trimester pregnancy loss were enrolled in the study. They were randomized in three groups;
misoprostol group in which 30 candidates were receive 2 tablets of misoprostol (i.e. 400 ug)
4 hrs prior to surgical evacuation, Effox group in which 30 candidates were received 2
tablets of Effox (i.e 40 mg) 4 hrs prior to surgical evacuation & combination therapy group
in which 30 candidates were received 1 tablets of misoprostol 200ug & 1 tablets of Effox 20
mg 4 hrs prior to surgical evacuation. For all participants, the route of administration was
the intravaginal route 1ry outcomes included cervical consistency & dilatation immediately
before the procedure. 2ry outcomes included total duration of the operation and the
occurrence of drug-related side effects