Misoprostol for Second Trimester Termination of Pregnancy

• Status: Completed
• Trial end date: 2005-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

To compare the efficacy of two different dose regimens of misoprostol administered vaginally in combination with mifepristone in second trimester termination of (non)viable pregnancy.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
• Treatments: Mifepristone; Misoprostol

Criteria

Inclusion Criteria:

• Women with a gestational age between 14 to 24 weeks, confirmed by ultrasound, requesting termination of pregnancy

Exclusion Criteria:

• No informed consent

• Mifepristone allergy

• Chronic adrenal gland failure

• Kidney failure

• Liver failure

• Chronic use of corticosteroids

• COPD not responsive to treatment

• Cardiovascular disease

• Glaucoma