Overview

Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia

Status:
Not yet recruiting
Trial end date:
2028-04-28
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to evaluate the effect of immunosuppressive therapy (IST) in participants treated with asfotase alfa who demonstrate immune-mediated loss of effectiveness (LoE).
Phase:
Phase 4
Details
Lead Sponsor:
Alexion Pharmaceuticals, Inc.
Treatments:
Bortezomib
Folic Acid
Methotrexate
Rituximab