Mitomycin and Mitoxantrone in Treating Patients With Acute Myelogenous Leukemia
Status:
Completed
Trial end date:
2000-08-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing
so they stop growing or die. Some cancers become resistant to chemotherapy drugs. Combining
mitomycin with a chemotherapy drug may reduce resistance to the drug and allow the cancer
cells to be killed.
PURPOSE: Phase I trial to study the effectiveness of mitomycin and mitoxantrone in treating
patients with acute myelogenous leukemia and to determine whether mitomycin can reduce the
cancer's resistance to chemotherapy.