Mode of Induction in Fetal Growth Restriction and Its Affects on Fetal and Maternal Outcomes

• Status: Unknown status
• Trial end date: 2021-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

to compare methods of induction of labor in fetal growth restriction and its effect on maternal and neonatal outcome

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tel-Aviv Sourasky Medical Center
• Treatments: Dinoprostone; Oxytocin

Criteria

Inclusion Criteria:

• singleton pregnancy

• fetal growth restriction defined as estimated fetal weight between the 3rd and 10th percentile per gestational age and are intended to deliver vaginally

• Gestational age between 36 and 42 weeks

• No known fetal anomalies

Exclusion Criteria:

• Fetal estimated weight below the 3rd percentile

• Known fetal anomalies

• Contraindications for vaginal delivery: breech presentation, abnormal Doppler flow velocimetry of fetal ductus venosus.

• Oligohydramnios defined as amniotic fluid index below 5 cm

• Contraindication to the use of prostaglandins

• Fetal distress requiring emergent cesarean section

• All other condition preventing vaginal delivery as decided by a senior physician