Urticaria is a common skin disorder and 15-25% of people experience at least one attack of
urticaria during their lifetime. Urticaria can be divided into acute urticaria (AU) and
chronic urticaria (CU). CU is more common in adults, and affects women more frequently than
men. According to Chinese medicine (CM) theory, CU is known as Yin Zhen. Nowadays, CM is
widely used for managing CU in Hong Kong and mainland. Among different Chinese herbal
formulae for urticaria, Xiao-Feng Powder (XFP), also known as Wind-Dispersing Powder, is one
of the most frequently used Chinese herbal formulae for CU.
This study used modified Xiao-Feng Powder (mXFP) to evaluate the effectiveness and safety of
mXFP in treating CU. Hence, a double-blind, randomised, placebo-controlled clinical trial
design with strong scientific rigor will be employed in this study, and it would be able to
provide robust clinical evidence on the efficacy and safety of mXFP for CU.