Modulation of Lactase Expression by a New PPARgamma Ligand in Duodenal Biopsies
Status:
Completed
Trial end date:
2017-09-01
Target enrollment:
Participant gender:
Summary
This study is designed to assess the effect of a new PPARgamma modulator on the expression
and activity of the lactase enzyme in human intestinal epithelial cells. Based on their
previous experimental results, the investigators hypothesized that modulating intestinal
PPARgamma activity is a new pharmacological mechanism allowing the control of lactase
expression and activity in the gut