Modulation of Mucosal and Systemic Immunity by Hormonal Contraceptives
Status:
Terminated
Trial end date:
2013-06-01
Target enrollment:
Participant gender:
Summary
The investigators are conducting a research study to understand how cells responsible for
fighting infection (immune cells) are affected by hormonal contraceptive use. The
investigators hypothesize that progestin-containing hormonal contraceptives (i.e.,
Depo-Provera) inhibit host response to infection. To test this hypothesis, the investigators
will collect blood and genital tract samples from women before and after their initiation of
a hormonal contraceptive (either birth control pills, Depo-Provera, or Mirena).
Details
Lead Sponsor:
Thomas Cherpes, DVM, MD
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)