Overview

Molecular Mechanisms of Antipsychotic-induced Insulin Resistance

Status:
Recruiting
Trial end date:
2024-07-01
Target enrollment:
Participant gender:
Summary
This study will investigate the molecular mechanisms of atypical-antipsychotic induced insulin resistance. This will be accomplished by administering olanzapine or placebo to healthy subjects for 7 days and analyzing genetic and protein changes in peripheral tissues known to play an important role in insulin resistance pathophysiology.
Phase:
Early Phase 1
Details
Lead Sponsor:
Wayne State University
Treatments:
Antipsychotic Agents
Olanzapine