Monolaurin Ointment Versus Mupirocin Ointment

• Status: Completed
• Trial end date: 2023-07-15
• Target enrollment: 0
• Participant gender: All

Summary

Skin infection remains one of the leading causes of pediatric consults especially in developing countries like the Philippines. This common condition has not been considered a significant problem that could cause alarm as public health importance. Furthermore, due to the consideration that skin diseases are benign, not life-threatening, and low priority.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Victoriano Luna Medical Center
• Treatments: Monolaurin; Mupirocin

Criteria

Inclusion Criteria:

• Subject aged 5 years old to 18 years old (school-aged children)

• Subjects has infected wound (laceration, sutured wound or abrasion), impetigo and other bacterial skin infections (positive gram stain or culture)

• Subject has total skin infection rating scale score of at least 4 including pus/exudate score of at least 1

• Subject parent/legal guardian is willing and able to comply with protocol (see attached consent)

• Subject parent/legal guardian has given written informed consent or assent as applicable.

• Patient has good hygiene

Exclusion Criteria:

• Previous hypersensitivity to Mupirocin

• Secondary- infected animal/human bite or punctured wound

• Subject has a large draining abscess

• Chronic ulcerative lesion

• Other underlying skin disease

• Patient is severely malnourished

• Systemic signs and symptoms of infection

• Infection not to be appropriately treated with topical antibiotic

• Infections requires surgical intervention prior to study

• Subject received systemic antibacterial or steroid, or topical therapeutic agent within 24 hours of entry into study

• Serious underlying medical conditions/ diseases (diabetes mellitus)

• Other investigational drug within 30 days of study entry.