Morphine Versus Methadone for Opiate Exposed Infants With Neonatal Abstinence Syndrome

• Status: Unknown status
• Trial end date: 2018-01-01
• Target enrollment: 0
• Participant gender: All

Summary

This study investigates the use of methadone versus morphine wean for the treatment of neonatal abstinence syndrome for infants exposed to opioids in utero. Half of infants who require pharmacotherapy for NAS will receive a methadone wean, and half will receive a morphine wean. Length of hospital stay, length of treatment and parent satisfaction will be studied.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of New Mexico
• Treatments: Methadone; Morphine

Criteria

Inclusion criteria:

• Born at University of New Mexico Hospital

• Greater than 34 weeks gestation

• Primary in-utero drug exposure was opioids other than buprenorphine

• Maternal or infant urine drug screen positive for methadone and/or opioids on admission

Exclusion criteria:

• Born prior to 34 weeks

• Neonatal intensive care unit admission

• Serious medical comorbidities

• Primary substance exposure in-utero was buprenorphine, or was not opioids