Morphine Versus Morphine-promethazine Combination for Acute Low Back Pain Relief in the Adult Emergency Department

• Status: Unknown status
• Trial end date: 2013-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Acute low back pain is a common cause for emergency department visits. Controversy remains regarding the optimal medication for acute low back pain relief. The investigators hypothesized that administration of pharmacological anxiolysis in addition to analgesia will improve pain relief and patient management in the emergency department.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tel-Aviv Sourasky Medical Center
• Treatments: Diphenhydramine; Morphine; Promethazine

Criteria

Inclusion Criteria:

1. An indication for opioid analgesia based in the ED (i.e. severe pain > 70mm on a 100mm VAS)

2. Age between 18-65 years

3. American Society of Anesthesiologists (ASA) score of 1 or 2, and no preexisting glaucoma, cardiac arrhythmia or pulmonary disease

4. Systolic blood pressure higher than 90 mmHg on admission

5. Willingness and ability to provide an informed consent

6. No known hypersensitivity to the medication used.

Exclusion Criteria:

1. Pregnant women

2. Patients who can not be under adult supervision following discharge from the emergency department.