Motor Response to Sildenafil in PD

• Status: Completed
• Trial end date: 2004-03-01
• Target enrollment: 0
• Participant gender: Male

Summary

Sildenafil (Viagra(R))is widely used by men with Parkinsons Disease (PD) and erectile dysfunction. A number of patients have reported that when they take Sildenafil, their need of anti-PD medication is reduced.

We hypotheses that sildenafil increases brain blood flow and hence improves the function of specific brain regions, improving motor function.

Motor function and cerebral blood flow of 8 patients will be tested before and after Sildenafil intake and before and after anti-PD medication.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bispebjerg Hospital
• Treatments: Sildenafil Citrate

Criteria

Inclusion Criteria:

• Men

• Parkinsons disease

• Erectile dysfunction

• previous tried sildenafil with beneficial effects on motor function

Exclusion Criteria:

• psychosis

• Heart disease