Moxibustion in Osteoarthritis of the Knee

• Status: Completed
• Trial end date: 2019-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a multicenter , double-blinded, double-dummy, randomized controlled clinical trial to evaluate the efficacy of moxibustion for osteoarthritis of the knee.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chengdu University of Traditional Chinese Medicine
• Treatments: Diclofenac

Criteria

Inclusion Criteria:

• Male or female, aged between 40 and 75 years, with knee osteoarthritis diagnosed according to American College of Rheumatology criteria

• Radiologic confirmation of osteoarthritis in 1 or both knees (Kellgren-Lawrence score 2 or 3)

• Had knee pain in one or both knee(s) of longer than 3 months'duration

• The average severity of knee pain at least 3 points on a10-point of visual analogue scale(VAS)

• Never experienced moxibustion before this trial

• Participants who are willing to comply with our study protocol

• Participants who agree to sign the consent form

Exclusion Criteria:

• Subjects with serious diseases including cancer, uncontrolled hypertension, diabetes mellitus requiring insulin injection, life-threatening cardiovascular or neurological events, chronic respiratory disease, a haemorrhagic disorder and serious mental diseases

• Subjects had pain in the knee may caused by inflammatory, malignant, autoimmune disease or traumatic injury;

• Subjects received knee replacement surgery for the affected knee

• Subjects received knee arthroscopy within the past year, steroid or hyaluronic acid injection in the knee joints within the previous 3 months

• Subject who currently participate in another clinical trial

• Subjects received physiotherapy or other treatments for osteoarthritis knee pain (with the exception of non-steroidal anti-inflammatory drugs) during the previous 4 weeks;