Moxifloxacin Plus Metronidazole Versus Piperacillin/Tazobactam for the Treatment of Patients With Intra-abdominal Abscesses
Status:
Completed
Trial end date:
2011-08-15
Target enrollment:
Participant gender:
Summary
The study is contemplating the antibiotic therapy of intraabdominal abscesses. These
abscesses are a serious problem in surgical practice. Associated pathophysiologic effects as
for example peritonitis may become life threatening or may lead to extended periods of
morbidity with prolonged hospitalization.
The objective of the sudy is to evaluate whether the combination of Moxifloxacin and
Metronidazole is equivalent to Piperacillin / Tazobactam with regard to clinical outcome and
eradication of aerobe and anaerobe pathogens in patients with intra-abdominal abscesses.
Phase:
Phase 3
Details
Lead Sponsor:
Hannover Medical School
Collaborator:
Bayer
Treatments:
Fluoroquinolones Metronidazole Moxifloxacin Norgestimate, ethinyl estradiol drug combination Penicillanic Acid Piperacillin Piperacillin, Tazobactam Drug Combination Tazobactam