Multi-Centre Trial Comparing Three Artemisinin-Based Combination Treatments on P. Falciparum Malaria
Status:
Completed
Trial end date:
2007-05-01
Target enrollment:
Participant gender:
Summary
The purpose of this open randomised multi-centre clinical trial is to test the hypothesis
that three pills of the fixed dose combination artesunate/sulfamethoxypyrazine/pyrimethamine,
administered over 24 hours is not inferior in efficacy to the same drug administered over 48
hours and that the fixed dose combination artesunate/sulfamethoxypyrazine/pyrimethamine
As/SMP fdc, independently of the duration of its dose interval, is not inferior in efficacy
to 6 - 24 pills (number of pills administered to respectively children and adults)of the 60
hours treatment of artemether/lumefantrine for the treatment of uncomplicated P. falciparum
malaria.