Overview Multi-center Clinical Study of Early Antibios of Severe Acute Pancreatitis Status: Unknown status Trial end date: 2016-12-01 Target enrollment: Participant gender: Summary Strategy of antibiotic therapy in SAP,De-escalate (cefoperazone+metronidazole) or Escalate (meropenem) therapy,which one is better. Phase: Phase 4 Details Lead Sponsor: Erzhen ChenCollaborator: RenJi HospitalTreatments: CefoperazoneChlorhexidineChlorhexidine gluconateMeropenemMetronidazoleSomatostatinSulperazoneThienamycins