Multi-strain Probiotic in the Management of IBS-D

• Status: Completed
• Trial end date: 2016-04-01
• Target enrollment: 0
• Participant gender: All

Summary

1. To assess the effect of multistrain probiotics on abdominal pain using a validated symptom severity score in IBS patients.

2. To assess the efficacy of a multi-strain probiotic supplement as a treatment option for IBS in a tertiary referral centre

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

Criteria

Inclusion Criteria:

1. Diagnosed case of IBS using Rome III criteria

2. Absence of red flag sign: anemia, fever, wt loss, per rectal bleeding, nocturnal frequency, family history of inflammatory bowel disease (IBD), cancer

3. Age 18-55 years

4. No probiotics used in prior 3 months.

5. Agreed not to start any other drug unless clinically indicated.

6. No antibiotics in previous 2 months of enrolment.

Exclusion Criteria:

1. Age<18 or >55 years

2. Previous treatment with probiotics within last 3 months

3. Pregnant or lactating females

4. Concurrent severe illness (Uncontrolled diabetes mellitus, Renal Dysfunction, Liver disease, hyper and hypothyroidism)

5. Chronic organic bowel disorders e.g. inflammatory bowel diseases, tuberculosis, Diverticular disease etc

6. Any previous gastrointestinal surgery