Overview Multicenter Interventional Lymphangioleiomyomatosis (LAM) Early Disease Trial Status: Recruiting Trial end date: 2023-06-30 Target enrollment: Participant gender: Summary This is a study to determine if early, long-term low dose sirolimus is effective for preventing progression to more advanced stages. Phase: Phase 3 Details Lead Sponsor: University of CincinnatiCollaborators: National Center for Advancing Translational Science (NCATS)National Heart, Lung, and Blood Institute (NHLBI)The LAM FoundationTreatments: EverolimusSirolimus