Multicenter Vitamin E Trial in Aging Persons With Down Syndrome
Status:
Completed
Trial end date:
2010-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the safety and effectiveness of 2,000 international
units of Vitamin E (alpha tocopherol)on cognitive function of aging persons with Down
syndrome. It is a randomized, double-blind, placebo-controlled trial lasting 36 months. It is
expected that Vitamin E will slow the deterioration in cognitive functions associated with
Alzheimer disease.
Phase:
Phase 3
Details
Lead Sponsor:
New York State Institute for Basic Research
Collaborators:
Bronx Veterans Medical Research Foundation, Inc Columbia University Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Center for Complementary and Integrative Health (NCCIH) National Institute on Aging (NIA) New York State Psychiatric Institute University of California, San Diego
Treatments:
alpha-Tocopherol Tocopherols Tocotrienols Vitamin E Vitamins