Overview

Multidisciplinary Approach for Poor Prognosis Sinonasal Tumors in Inoperable Patients

Status:
Active, not recruiting
Trial end date:
2024-01-01
Target enrollment:
Participant gender:
Summary
Sinonasal tumors are rare diseases, as they account for the 0.2 % - 0.8 % of all tumors. For patients with inoperable tumors, the prognosis is poor and the current therapy is a combined-modality treatment that is both more effective and associated with less morbidity. This study proposes innovative integration of multiple modality of treatment modulated by histology, molecular profile and response to induction CT.
Phase:
Phase 2
Details
Lead Sponsor:
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Collaborator:
Regione Lombardia
Treatments:
Cisplatin
Docetaxel
Doxorubicin
Etoposide
Etoposide phosphate
Fluorouracil
Ifosfamide
Isophosphamide mustard
Leucovorin
Liposomal doxorubicin