Multimodal Pain Package vs. Regular Formulation for Pain Management in Ambulatory Spinal Surgery

• Status: Not yet recruiting
• Trial end date: 2025-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this research is to compare two outpatient pain management strategies in patients undergoing spinal surgeries such as microdiscectomies, foraminotomies, and spinal decompressions.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Miami
• Treatments: Acetaminophen; Celecoxib; Famotidine; Gabapentin; Oxycodone

Criteria

Inclusion Criteria:

• Adults: males or non-pregnant females.

• Patients undergoing ambulatory microdiscectomies, foraminotomies, and spinal cord decompressions requiring pain control analgesics.

Exclusion Criteria:

• Pregnancy

• Active severe liver disease

• Chronic kidney disease 3a-5 (moderate to severe)

• Chronic obstructive pulmonary disease with impaired pulmonary function

• Chronic steroid use

• Chronic opioid use

• Current use of narcotics

• Allergy to sulfonamides

• Allergy to NSAIDs

• Allergy to Aspirin

• Allergy to Tylenol

• Allergy to Gabapentins

• Allergy to H2 blockers (cimetidine, famotidine)

• Allergy to steroid

• Current use of gabapentins for any medical condition

• Inability to be discharged home on the day of surgery

• Inability to swallow pills

• Myasthenia gravis

• History of gastrointestinal ulcers or stomach bleeding

• Have any condition that, in the investigator's opinion, will compromise the well-being of the patient or the study, or prevent the patient from meeting or performing study requirements.