Multiparametric MRI Study of Endogenous Analgesia and Prediction the Efficacy of Migraine Pharmacological Prevention
Status:
Completed
Trial end date:
2017-11-06
Target enrollment:
Participant gender:
Summary
To delineate brain mechanisms that subserve EA in the healthy state and to identify
alterations in mechanisms supporting EA in chronic pain and their therapeutic relevance.
Individuals with migraine will be examined between episodes in order to assess basal
alterations in the efficiency of spatial and temporal filtering of noxious information. This
population provides the unique opportunity to examine such processes without confounds
arising from ongoing pain.