Multiple Dose Effects of Hydrochlorothiazide and Isosorbide Mononitrate on Glucose Homeostasis (MK-0000-117)(Completed)
Status:
Completed
Trial end date:
2010-03-01
Target enrollment:
Participant gender:
Summary
This study will measure and compare changes in insulin production and sensitivity using the
hyperglycemic clamp technique in obese patients with impaired glucose tolerance and
hypertension treated with placebo, isosorbide mononitrate (ISMN) or hydrochlorothiazide
(HCTZ).