Multivariable Assessment of Coronary Artery Disease Using Cardiac CT Imaging

• Status: Completed
• Trial end date: 2013-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators goals are:

1. to develop software for quantitative volumetric analysis of myocardial perfusion from MDCT images

2. to test its ability to accurately determine the presence, location, extend and severity of perfusion abnormalities in agreement with conventional diagnostic techniques (ICA and MPI) in patients with normal and abnormal coronary arteries and/or perfusion patterns

3. to test this approach in patients undergoing vasodilator stress tests with MDCT imaging in combination with the new vasodilator stress agent Regadenoson.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Chicago
• Collaborator: Astellas Pharma Inc
• Treatments: Regadenoson

Criteria

Inclusion Criteria:

• 18 years and older

• Subjects referred for clinically indicated cardiac CT exams

Exclusion Criteria:

• Subjects with a history of lung disease

• Pregnant subjects

• Subjects with second or third degree AV block or sinus node dysfunction